Gale fundamentals of micromachining microfluidic system concept concept one system to provide all of the possible required analyses for a given type problem all processing steps are performed on the chip no user interaction required except for initialization portable bedside systems possible labonachip. Deguang yan, chun yang, jianmin miao, yeecheong lam, xiaoyang huang. Experimental and numerical investigation into the joule heating effect for electrokinetically driven microfluidic chips utilizing total internal reflection fluorescence microscopy. Exosomes are a specific subpopulation of extracellular vesicles that have gained interest because of their many potential biomedical applications. Enhancement of electrokinetically driven microfluidic tmixer using frequency modulated electric field and channel geometry effects. The transport of counterions along with the pressure driven fluid flow gives rise to a net charge transport. Chang, h and yeo, l 2010, electrokinetically driven microfluidics and nanofluidics, cambridge university press, new york, united states. Pdf the applications of electrokinetics in the development of microfluidic devices have been widely. A typical setup to measure streaming currents consists of two reversible electrodes. Electrokinetic phenomena in pencil leadbased microfluidics mdpi.
This site is like a library, use search box in the widget to get ebook that you want. Microfluidics and nanofluidics, volume 5, issue 6 springer. Electrokinetically driven microfluidics and nanofluidics, cambridge university press, new york, 2010. The surface charge and potentials are depicted based on the theories developed over the past century figure from 1 surfacemodified microfluidics and nanofluidics 26 s s. Microfluidic devices for electrokinetically driven parallel and serial. Jul 28, 2019 electrokinetically driven microfluidics and nanofluidics rmit research repository electrokineticallydriven microfluidics and nanofluidics. An electrokinetically driven deterministic lateral displacement edld device is proposed for the continuous, twodimensional fractionation of suspensions in microfluidic platforms. Electrokinetically driven flow reversepolarity substrate material.
Electrokinetic particle transport in micronanofluidics. Electrokinetically driven microfluidics and nanofluidics rmit research repository this text aims to provide a comprehensive treatise on both classical equilibrium electrokinetic phenomena as well as the more recent nonequilibrium phenomena associated with both dc and ac electrokinetics in the context of their application to the design of. Electrokinetically driven microfluidics and nanofluidics pdf electrokinetically driven microfluidics and nanofluidics hsuehchia chang, university of notre dame, leslie y. Dielectrophoresis assembling cancer cells in a 3d microfluidic model. Pdf on jun 1, 2009, leslie yeo and others published advances in microfluidics and nanofluidics find, read and cite all the research you need on researchgate.
Microfluidics and nanofluidics download ebook pdf, epub. Pressuredriven flows of fixed flow rates were provided by an infusion. Electrokinetically driven microfluidics and nanofluidics rmit. Mar 01, 2010 9780521860253 electrokinetically driven microfluidics and nanofluidics. Click download or read online button to get microfluidics and nanofluidics book now. In particular, electrokineticaloy yeo and hsuehchia chang discuss the linear and nonlinear theories underlying electroosmosis, electrophoresis, and dielectrophoresis pertaining to electrolytes as well. Open microfluidic devices are also easy and inexpensive to fabricate by milling, thermoforming, and hot embossing. There has recently been widespread interest in the use of ac electric.
Microfluidic devices for electrokinetically driven parallel and serial mixing. Jun 19, 2019 brentano psychologie vom empirischen standpunkt pdf. The suspended species are driven through an array of regularly spaced cylindrical posts by applying an electric field across the device. Electrokinetically driven microfluidics and nanofluidics, cambridge.
Amazon renewed refurbished products with a warranty. In particular, electrokineticaloy yeo and hsuehchia chang discuss the linear and nonlinear theories underlying electroosmosis, electrophoresis, and dielectrophoresis pertaining to electrolytes as well as dielectric systems. Fluid motion in these chemical biochip systems is often achieved using electroosmotic flow. Those who suffer from the disease to please are people who say yes when they really want to say no. Electroosmotic flow or electro osmotic flow, often abbreviated eof. Nanofluidic devices have unique capabilities for manipulation and sensing of dna molecules at the singlemolecule level. Microfluidic system concept concept one system to provide all of the possible required analyses for a given type problem all processing steps are performed on the.
Electrokinetically driven microfluidics and nanofluidics. He has delivered several named lectures and keynote speeches, including the colburn lecture at the university of delaware, the corrsin lecture at johns hopkins, the pattern lecture at university of colorado and. Sorry, we are unable to provide the full text but you may find it at the following locations. Pdf electrokinetic mixing in microfluidic systems researchgate. Jan 28, 2020 electrokinetically driven microfluidics and nanofluidics rmit research repository this text aims to provide a comprehensive treatise on both classical equilibrium electrokinetic phenomena as well as the more recent nonequilibrium phenomena associated with both dc and ac electrokinetics in the context of their application to the design of. Occasional negative moods as opposed to major clinical depression should not be cause for alarm, according to clinical psychologist braiker. Electrokinetically driven microfluidics and nanofluidics rmit research repository this text aims to provide a comprehensive treatise on both classical equilibrium electrokinetic phenomena as well as the more recent nonequilibrium phenomena associated with both dc and ac electrokinetics in the context of their application to the design of microfluidic and nanofluidic technology. Electrokinetics is currently the mechanism of choice for fluid actuation and bioparticle manipulation at microscale and nanoscale dimensions. In particular, leslie yeo and hsuehchia chang discuss the linear and nonlinear theories underlying electroosmosis, electrophoresis, and dielectrophoresis pertaining to. Lab chip 14, 18021805 2014 pdf article coverart selected for journal back cover p.
Electrokinetic flow diagnostics stanford university. This work presents a direct currentinsulatorbased dielectrophoretic dcidep approach to simultaneously capture and separate exosomes by size. Electrokinetically driven microfluidics and nanofluidics electrokinetics is currently the mechanism of choice for. All particles exhibit dielectrophoretic activity in the presence of. Surface tensiondriven flow surface tensionpowered self. Journal of microfluidics and nanofluidics journal metrics 2015 days from submission to first decision number of days from submission of a manuscript to first decision. Equivalent circuit modeling of electrokinetically driven analytical microsystems. Influence of surface heterogeneity on electrokinetically.
Electrokineticallydriven deterministic lateral displacement. Nielsen book data summary electrokinetics is currently the mechanism of choice for fluid actuation and bioparticle manipulation at microscale and nanoscale dimensions. Design optimization of an enzymatic assay in an electrokinetically driven microfluidic device y. Objectives the primary objectives of the course are as follows. Electrokinetically driven microfluidic chips with surface. To simplify the voltage control hardware, electrokinetic mixing is. The reverse effect, generating a fluid flow by applying a potential difference, is called electroosmotic flow.
This force does not require the particle to be charged. Nanofluidics have had a significant impact in biotechnology, medicine and clinical diagnostics with the development of labonachip devices for pcr and related techniques. Another advantage of open microfluidics is the ability to integrate open systems with surfacetension driven fluid flow, which eliminates the need for external pumping methods such as peristaltic or syringe pumps. Leslie yeo author of electrokinetically driven microfluidics. Leslie yeo is the author of a thousand and one first nights 0. Dielectrophoresis dep is a phenomenon in which a force is exerted on a dielectric particle when it is subjected to a nonuniform electric field. Dec 06, 2008 design optimization of an enzymatic assay in an electrokineticallydriven microfluidic device y. Electrokinetically driven microfluidics and nanofluidics rmit research repository electrokinetically driven microfluidics and nanofluidics. Electrohydrodynamic atomization, electrospinning and discharge driven vortices.
There has recently been widespread interest in the use of ac electric fields, given the many advantages it offers over dc electrokinetics. Buy electrokineticallydriven microfluidics and nanofluidics on. The electrokinetic phenomena were characterized by microparticle image. Providing the basic knowledge on the underlying physics of electrokinetically driven flow at microscale level. Electrokinetically driven microfluidics and nanofluidics in. Microfluidics and nanofluidics, volume 11, number 5, 537544, 2011. Electrokinetically driven microfluidics and nanofluidics cambridge univ press, 2009. Disruption of longterm electrokinetic transients in pressure driven flow via a. Electrokinetically driven microfluidics and nanofluidics core. Electrokinetically driven microfluidics and nanofluidics rmit research repository. Microfluidic and nanofluidic devices and systems are. However, exosome isolation and characterization are the first steps toward designing novel applications. Nov 30, 2009 electrokinetically driven microfluidics and nanofluidics by hsuehchia chang, 9780521860253, available at book depository with free delivery worldwide. Gateable nanofluidic interconnects for multilayered microfluidic.
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